Agitoxin
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Details
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Agitoxin is a toxin found in the venom of the scorpion Leiurus quinquestriatus herbraeus (yellow scorpion). Agitoxin binds to the Shaker K+ channel in Drosophila as well as to its mammalian homologue. It blocks this channel by binding with high affinity (Kd 1 nmol/L) to its external vestibule.Agitoxin can be purified using HPLC techniques. Its structure consists of a triple-stranded antiparallel beta-sheet and a single helix covering one face of the beta-sheet. The cysteine side chains connect the beta-sheet and the helix form to the core of the molecule. The fold of agitoxin is homologous to the previously determined folds of scorpion venom toxins.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786138084587
- Editor Columba Sara Evelyn
- Sprache Englisch
- Auflage Aufl.
- Größe H229mm x B152mm x T5mm
- Jahr 2011
- EAN 9786138084587
- Format Kartonierter Einband (Kt)
- ISBN 978-613-8-08458-7
- Titel Agitoxin
- Untertitel Toxin, Venom, Drosophila, Deathstalker
- Gewicht 127g
- Herausgeber FEC PUB
- Anzahl Seiten 80
- Genre Biologie
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