Bio-targeted study on plant extracts with periodontal application

Periodontal disease is an infectious, painless and slowly progressive oral disease with a high incidence worldwide. Among the associated pathogenic flora is the anaerobic bacterium Porphyromonas gingivalis, which has also been associated as an inducer of coronary lesions, pneumonia and pre-eclampsia. In this study, four plant species from northern Mexico were analysed: Krameria ramosissima, Larrea tridentata, Jatropha dioica and Leucophyllum frutescens, from which their extracts were obtained by the continuous extraction technique using methanol as solvent; their yields were obtained and chemical tests were performed for preliminary identification of compounds. Cytotoxicity and mutagenicity tests were carried out on the most active compounds.

Autorentext

L'auteur principal est chirurgien-dentiste et titulaire d'une maîtrise en santé publique. Il a récemment obtenu son doctorat en sciences avec une spécialisation en chimie des produits naturels à la Faculté des sciences biologiques de l'UANL. Il est actuellement professeur de recherche à plein temps à la faculté de médecine dentaire de l'UANL.