Biofilm

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A biofilm is an aggregate of microorganisms in which cells are stuck to each other and/or to a surface. These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance (EPS). Biofilm EPS, which is also referred to as "slime," is a polymeric jumble of DNA, proteins and polysaccharides. Biofilms may form on living or non-living surfaces, and represent a prevalent mode of microbial life in natural, industrial and hospital settings. The cells of a microorganism growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which by contrast, are single-cells that may float or swim in a liquid medium. Microbes form a biofilm in response to many factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics. When a cell switches to the biofilm mode of growth, it undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated.
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Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786130271039
    • Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
    • Sprache Englisch
    • Jahr 2010
    • EAN 9786130271039
    • Format Fachbuch
    • ISBN 978-613-0-27103-9
    • Titel Biofilm
    • Untertitel Microorganism, Plankton, Phenotype, Regulation of gene expression, Bacterial mat, Phototrophic biofilms, Stromatolite, Neisseria gonorrhoeae, Cell adhesion, Antibiotic resistance
    • Herausgeber Alphascript Publishing
    • Anzahl Seiten 88
    • Genre Biologie

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