Biophotonics: Spectroscopy, Imaging, Sensing, and Manipulation

This volume describes an impressive array of the photonic-related technologies being used to investigate biological systems, and includes an overview of the field by biophotonics luminary Paras Prasad. It also covers in detail the physics behind these tools.

This volume describes an impressive array of the current photonic-related technologies being used in the investigation of biological systems. The topics include various types of microscopy (fluorescence correlation microscopy, two-photon microscopy), sensitive detection of biological molecules, nano-surgery techniques, fluorescence resonance energy transfer, nano-plasmonics, terahertz spectroscopy, and photosynthetic energy conversion. The emphasis is on the physical principles behind each technique, and on examining the advantages and limitations of each.The book begins with an overview by Paras Prasad, a leader in the field of biophotonics, of several important optical techniques currently used for studying biological systems. In the subsequent chapters these techniques are discussed in depth, providing the reader with a detailed understanding of the basic physical principles at work. An excellent treatment of terahertz spectroscopy demonstrates how photonics is being extended beyond the visible region. Recent results in the use of femtosecond lasers as a tool to porate cell walls demonstrate that the manipulation of light can be used as a tool for the study and the treatment of biological systems. The field of Bio-photonics is broad and still growing, so cannot be covered comprehensively in one volume. But here the reader will find an introduction to some of the major tools used for studying biological systems, and at the same time a detailed, first-principles treatment of the physics behind these tools.

The material has already been presented in lectures at a NATO ASI meeting It presents photonic devices used for a wide variety of applications to biological systems Spectroscopy, imaging, sensing, and manipulation - all in one book A first-principles, detailed approach provides a solid physics background to each topic Presents latest results by authors working in several different sub-fields of bio-photonics Includes supplementary material: sn.pub/extras

Inhalt
Preface. List of Advanced Study Institutes; Lectures. Biophotonics: Harnessing Light for Biology and Medicine-.Nano-Plasmonics for Bio-Photonics.- Photons and Photon Correlation Spectroscopy.- Principles and Applications of Fluorescence Correlation Spectroscopy (FCS).- Nanoscopy Using Localization and Temporal Separation of Fluorescence from Single Molecules.- Fluorescence Spectroscopy and Energy Transfer Processes in Biological Systems.- Fluorescence of Strongly Absorbing Multicomponent Media.- Coherent Quantum Control in Biological Systems.- Subcellular Surgery and Nanono-Surgery Using Femtosecond Laser Pulses.- Solar Energy Conversion Natural to Artificial.- Whispering Gallery Mode Biosensor.- Two-Photon Absorption and Applications to Biological Systems.- Terahertz Spectroscopy of Biological Systems.- Laser-Produced Plasmas for Bio-Photonics.- Real-Time Spectroscopy of Solid-State Random Lasers.- Interdisciplinary Lecture. Neutrinos in Particle Physics and Astrophysics.- Short Seminars. Poster Presentations. Summary of the Erice School. List of Participants. Index.