Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics

Provides an introduction to nanomedicine and cancer therapy before exploring important biomedical applications
Provides a pathway to future studies on the synthesis and surface modification of nanomedicine in the cancer therapy field
Explores novel hybrid nanomaterials for efficient designing of multifunctional nanoflotillas

Autorentext
Ravichandran Manisekaran received his degrees from Thiruvalluvar Univeersity, B.Sc in Biochemistry (2008) and M.Sc. in Medical Bionanotechnology from Chettinad University (2010). Recently, he received his PhD in the field of Nanoscience and Nanotechnology (March 2017), from the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Zacatenco, Mexico City. He will be joining as a research associate in the Nanobio-optics laboratory, Center for Applied Physics and Advanced Technology (CFATA), UNAM campus, Juriquilla. His current research interests are focused on the use of surface functionalized multifunctional nanoparticles for various biomedical applications such as targeted drug delivery, hyperthermia, contrast agents, thermal ablation, electrospinning and biosensing. He was awarded a CONACYT fellowship for carrying out his doctoral research in CINVESTAV-IPN from 2013-2017.

Inhalt
Introduction to Nanomedicine and Cancer Therapy.- Literature Survey on Magnetic, Gold and Core-Shell Nanoparticles.- Characterization Techniques, Cell Cultivation and Experimental Setup.- Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-delivery and Apoptosis Induction in Cancer Cells.- Multiple Iterative Seeding of Surface Plasmon Enhanced Cobalt-Iron Oxide Nanokernels for Cancer Theranostics.- Nano-flotillas MnFe2O4@Au Core-shell Nanoparticles: An Efficient MRI Contrast Agent, Magneto-hyperthermal and Drug-delivery Armada for Cancer.- Concluding Remarks and Future Prospects.