Human Leukocyte HLA-B7 and HLA-B27 Antigen Typing Among Healthy Adults

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Details

The human leukocyte antigens are genetically inherited proteins present on the surface of the cells of the immune system. Cells of the immune system recognize antigens only when presented to them next to an MHC self-molecule. Three main types of HLA Class I namely, HLA-A, HLA-B and HLA-C they are expressed by most human cells. Class I HLAs are involved in discriminating and presenting antigens to T-lymphocytes. T-lymphocytes kill the cell presenting it. T-lymphocytes destroy cells infected together with viruses, including HIV. Developing a vaccine for HIV may be aided by a complete understanding of those rare cases in which some HIV-infected individuals control replication of the virus. Most of these elite controllers express the histocompatibility alleles HLA-B57 or HLA-B27, these alleles remain the most robust associations with low concentrations of plasma virus.

Autorentext

Francis Millinga lavora presso il Dipartimento di Biochimica della Muhimbili University of Health and Allied Sciences. Said Aboud lavora presso il Dipartimento di Microbiologia e Immunologia ed Erasto Mbugi presso il Dipartimento di Biochimica della Muhimbili University of Health and Allied sciences.

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Weitere Informationen

  • Allgemeine Informationen
    • Sprache Englisch
    • Herausgeber LAP LAMBERT Academic Publishing
    • Gewicht 96g
    • Untertitel Primed With HIV-1 DNA Boosted With Recombinant Modified Vaccinia Ankara in Dar es Salaam
    • Autor Francis Millinga , Said Aboud , Erasto Mbugi
    • Titel Human Leukocyte HLA-B7 and HLA-B27 Antigen Typing Among Healthy Adults
    • Veröffentlichung 24.05.2018
    • ISBN 6139824907
    • Format Kartonierter Einband (Kt)
    • EAN 9786139824908
    • Jahr 2018
    • Größe H220mm x B150mm x T4mm
    • Anzahl Seiten 52
    • GTIN 09786139824908

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