Introduction of Coumarin

The importance of Coumarin as anticoagulant dicoumarol by a number of species of fungi. This occurs as the result of the production of 4-hydroxycoumarin, then further (in the presence of naturally occurring formaldehyde) into the actual anticoagulant dicoumarol, a fermentation product and mycotoxin. Dicoumarol was responsible for the bleeding disease known historically as "sweet clover disease" in cattle eating moldy sweet clover silage.In basic research, preliminary evidence exists for coumarin having various biological activities, including anti-inflammatory, anti-tumor, antibacterial, and antifungal properties, among others.

Autorentext

L'auteur Parin Shaikh est titulaire d'une maîtrise en chimie (chimie organique) du département de chimie de l'université Sardar Patel, VV Nagar, Anand. L'auteur s'est vu décerner un doctorat pour la thèse qu'il a soumise et qui s'intitule "synthèse, caractérisation et criblage antimicrobien de benzofuranyl styryl pyridine/ pyrazolyl pyrazoline coumarins".