Investigating Virus Transmission in HTLV-1 Infected People

Human T-Cell lipotropic virus type I (HTLV-I) is the first human retrovirus that was discovered in 1980 in America in Dr. Callo's laboratory by Powez. In that history, Dr. Powez and his colleagues studied a patient with skin lymphoma. In this study, they concluded that patients infected with HTLV-1 have a poor oral and dental health status compared to the other group, and also observed a weak positive relationship between viral load in blood and saliva, and also a direct relationship between viral load found in saliva with oral manifestations.Martin S and his colleagues in a study in 2010 investigated the oral clinical manifestations of HTLV-1 infection in Brazilian adult patients. They studied 139 patients, of which 112 patients had HTLV-1 and 26 patients had HTLV- 2 and 1 patient had both HTLV-1 and HTLV-2 diseases. The most common clinical manifestations observed in these patients included rhizostomia, candida, furrowed tongue and lack of lingual papilla.

Autorentext
Omid GholizadehDepartment of Bacteriology and Virology, Faculty of Medical Sciences, Tabriz University of Medical Sciences, IranHamed AfkhamiDepartment of Medical Microbiology, Faculty of Medicine, Shahed University of Medical Science, IranShirin MalehmirCellular and Molecular biology, Islamic Azad University, Karaj Branch, Iran