Myosin Light and Heavy Chain Isoforms: Endurance Training

This study investigated the differences in the
relative
content of MyLC and MyHC slow and fast isoforms
between fast-twitch and slow-twitch skeletal
muscles. In particular, it examines the effect of
endurance training, an increase in the training
volume on the MyLC and MyHC relative content,
turnover rate and regeneration after muscle
grafting.Parallel changes of MyLC and MyHC isoforms
in fast-twitch and slow-twitch skeletal muscles, and
in fast-twitch muscles with different oxidative
potential, occuring in response to endurance
training may point to functional significance of
each isoform in the process of adaptation of the
contractile apparatus to muscular activity.
Exhaustive exercise causes destruction in
contractile machinery and decreases the turnover
rate of contractile proteins. These results should
help to answer questions related to the effect of
endurance training volume on the character of
skeletal muscle kinetics, related with differences
in molecular motors in different types of muscles.
This book is addressed to coaches, researchers in
sports and exercise science,experts in sports
medicine and students.

Autorentext

Karin Alev, MSc,PhD: studied Physics and Chemistry at University of Tartu. Research area is determination of the physiological factors that regulate the expression of specific isoforms of contractile proteins.Currently senior researcher at the University of Tartu.

Klappentext

This study investigated the differences in the relative content of MyLC and MyHC slow and fast isoforms between fast-twitch and slow-twitch skeletal muscles. In particular, it examines the effect of endurance training, an increase in the training volume on the MyLC and MyHC relative content, turnover rate and regeneration after muscle grafting.Parallel changes of MyLC and MyHC isoforms in fast-twitch and slow-twitch skeletal muscles, and in fast-twitch muscles with different oxidative potential, occuring in response to endurance training may point to functional significance of each isoform in the process of adaptation of the contractile apparatus to muscular activity. Exhaustive exercise causes destruction in contractile machinery and decreases the turnover rate of contractile proteins. These results should help to answer questions related to the effect of endurance training volume on the character of skeletal muscle kinetics, related with differences in molecular motors in different types of muscles.This book is addressed to coaches, researchers in sports and exercise science,experts in sports medicine and students.