Nasal carriage of Staphylococcus aureus

Staphylococcus aureus is a common cause of disease, particularly in colonized persons.259 nasal swabs were collected from 127 females and 132 males between age 3-15 years in primary and secondary schools in Ile- Ife, Osun state. The nasal carriage rate by the subjects was influenced primarily by age and found to be 33.3% in ages 3-5 years, 28.3% in ages 6-8 years, 24.1% in ages 9-11 years and 18.1% in ages 12-15 years showing a decreasing nasal carriage rate with increasing age of which there was a significant difference within the age groups of the subjects without significant difference of the nasal carriage of S.aureus in females and males at 5% level of significance and the overall nasal carriage of S.aureus is 22.0%. Resistance and susceptibility patterns to commonly used antibiotics in the community environment were determined, of which 94.6% of the S. aureus isolates were resistant to Ampicillin, 61.8% to Trimethoprim,60.0% to Tetracycline,9.1% to Chloramphenicol,3.6% to each of Sulphonamide and Streptomycin,and 1.8% to each of Ciprofloxacin and Cefoxitin. The clinical implication of this result is that students of lower age group are more susceptible to S.aureus infections.

Autorentext

Mrs. Olaniyan(nee Fakunle) Esther Omowumi is a graduate of Pharmacy from Obafemi Awolowo University, Ile Ife, Osun State, Nigeria.She is married to Mr. Olaniyan Samson Olajide.