Neuromyotonia
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Neuromyotonia, also known as Isaacs'' Syndrome, is spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin. It develops as a result of both acquired or hereditary diseases. Acquired form is more frequent and is usually caused by antibodies against neuromuscular junction. Autoreactive antibodies can be detected in a variety of peripheral (e.g. myasthenia gravis, Lambert-Eaton myasthenic syndrome) and central nervous system (e.g. paraneoplastic cerebellar degeneration, paraneoplastic limbic encephalitis) disorders. Their causative role has been established in some of these diseases but not all. Neuromyotonia is considered to be one of these with accumulating evidence for autoimmune origin over the last few years. Some neuromyotonia cases do not only improve after plasma exchange but they may also have antibodies in their serum samples against voltage-gated potassium channels. Moreover, these antibodies have been demonstrated to reduce potassium channel function in neuronal cell lines.
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GarantieWeitere Informationen
- Allgemeine Informationen
- Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
- Titel Neuromyotonia
- Format Fachbuch
- EAN 9786130975982
- Größe H220mm x B220mm
- Genre Medizin
- Anzahl Seiten 84
- Herausgeber Betascript Publishing
- GTIN 09786130975982
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