USO1
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High Quality Content by WIKIPEDIA articles! General vesicular transport factor p115 is a protein that in humans is encoded by the USO1 gene. The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
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GarantieWeitere Informationen
- Allgemeine Informationen
- GTIN 09786131497353
- Genre Technik
- Editor Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
- Anzahl Seiten 136
- Herausgeber Betascript Publishing
- EAN 9786131497353
- Titel USO1
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