X-inactivation

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High Quality Content by WIKIPEDIA articles! X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by packaging into transcriptionally inactive heterochromatin. X-inactivation occurs so that the female, with two X chromosomes, does not have twice as many X chromosome gene products as the male, which only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as mice and humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.
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Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786130488413
    • Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
    • EAN 9786130488413
    • Format Fachbuch
    • Titel X-inactivation
    • Herausgeber Betascript Publishing
    • Anzahl Seiten 100
    • Genre Biologie

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