XIST (Gene)
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Details
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. X (inactive)-specific transcript, also known as XIST, is a human gene. X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females (see dosage compensation). The process is regulated by several factors, including a region of chromosome X called the X inactivation center (XIC). The XIST gene is expressed exclusively from the XIC of the inactive X chromosome. The transcript is spliced but apparently does not encode a protein. The transcript remains in the nucleus where it coats the inactive X chromosome. Alternatively spliced transcript variants have been identified, but their full length sequences have not been determined.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786130951504
- Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
- Größe H220mm x B220mm
- EAN 9786130951504
- Format Fachbuch
- Titel XIST (Gene)
- Herausgeber Betascript Publishing
- Anzahl Seiten 124
- Genre Biologie
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