Epithelial sodium channel

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High Quality Content by WIKIPEDIA articles! The epithelial sodium channel (short: ENaC, also: sodium channel non-neuronal 1 (SCNN1) or amiloride sensitive sodium channel (ASSC)) is a membrane-bound ion-channel that is permeable for Li+-ions, protons and especially Na+-ions. It is a constitutively active ion-channel. It is arguably the most selective ion channel. The apical membrane of many tight epithelia contains sodium channels that are primarily characterised by their high affinity to the diuretic blocker amiloride. These channels mediate the first step of active sodium reabsorption essential for the maintenance of body salt and water homeostasis. In vertebrates, the channels control reabsorption of sodium in kidney, colon, lung and sweat glands; they also play a role in taste perception.

Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786130856502
    • Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
    • EAN 9786130856502
    • Format Fachbuch
    • Titel Epithelial sodium channel
    • Herausgeber Alphascript Publishing
    • Anzahl Seiten 76
    • Genre Biologie

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