Advances in Corneal Research

These Proceedings of the Fourth International Congress on the Cornea continue a tradition of summarizing the state-of-the art basic and clinical research in cornea and ex ternal diseases since the first Congress was held in 1964. Reflecting the emerging impor tance of refractive surgery, two of the twelve sessions of the Congress were devoted to refractive surgery; this is reflected in an emphasis in these Proceedings. In addition, an en tire session was devoted to the molecular and cellular biology of the cornea with impor tant new information on the role of growth factors and cytokine modulation of corneal wound healing. Within these Proceedings an international group of expert researchers and practitioners provide the latest insights into the tear film and ocular surface, corneal trans plantation and eyebanking, the corneal stroma and endothelium, contact lenses, microbial and nonmicrobial keratitis, keratoconus, and world corneal health. Notable subjects covered include the latest understanding of the barrier function of the ocular surface epithelium, corneal hydration control, the molecular mechanisms con trolling gene expression in corneal wound healing, stromal~pithelial interactions in the cornea, the immunology of blepharitis, the effect of contact lenses on the conjunctiva, morphologic and functional evaluation of the human corneal endothelium, long-term fol low-up of penetrating keratoplasty in keratoconus, the Tampa trephine penetrating kerato plasty, and the refractive results of the Nidek EC-5000 excimer laser.

Zusammenfassung
`Almost every aspect of corneal research and clinics is discussed in a large number of papers. This publication should be known to everyone interested in corneal clinics or research.'
Acta Ophthalmologica Scandinavica (1999)

Inhalt
Session I. Ocular Surface, Lids, Tears.- 1. The Evolution of Lid Margin Changes in Blepharitis.- 2. Immunology and Therapy of Marginal Ulceration as a Complication of Chronic Blepharitis Due to S. aureus.- 3. Meibomian Marginal Dimples: Clinical Indicants of Reactive Pathogenic Processes.- 4. Developing the Optimal Artificial Tear.- 5. Barrier Function of Ocular Surface Epithelium.- 6. Clinical Assessment of Conjunctival Damage and Tear Film Stability in Drug-Induced Epithelial Keratopathy.- 7. Corneal Epithelial Rejection after Allograft Conjunctival Transplantation for Limbal Papilloma: A Case Report.- 8. Automated Extraction of Morphological and Morphometric Characteristics of the Conjunctival Vasculature.- 9. Impression Cytology of the Conjunctiva in AIDS Patients: Goblet and Orange Cells Analysis.- 10. Response of the Ocular Surface to Histamine.- 11. Botulinum Toxin Treatment for Filamentary Keratitis Associated with Corneal Occlusion by Lids.- 12. Clinical Uses of Human Amniotic Membrane for Ocular Surface Diseases.- 13. Differential Diagnosis between Corneal Intraepithelial Neoplasia and Conjunctival Epithelial Invasion by Impression Cytology.- 14. Frozen Section Guided Lamello-Lamellar Sclerokeratoplasty in Squamous Cell Carcinoma of Conjunctiva and Cornea.- Session II. Corneal Transplantation and Eye Banking.- 15. Stromal Hydrodelamination Technique in Deep Lamellar Keratoplasty with Complete Removal of Pathologic Stroma.- 16. Indications and Results of Keratoplasty A Chaud.- 17. Langerhans Cells in the Recipient Cornea as Prognostic Indicator in Corneal Transplantation.- 18. Tampa Trephine Penetrating Keratoplasty: Results of the First 35 Cases.- 19. Penetrating Keratoplasty for Pseudophakic Bullous Keratopathy: An Indian Experience.- 20. PenetratingKeratoplasty for Bullous Keratopathy after Argon Laser Iridotomy.- 21. Intraoperative Use of Tissue Plasminogen Activator for Cornea Transplant Surgery.- 22. Surgical Treatment of Castroviejo Urrets-Zavalia Syndrome.- 23. Postoperative Endophthalmitis and Intraocular Vancomycin.- Session III. Corneal Stroma and Endothelium.- 24. An Update on Corneal Hydration Control.- 25. Corneal Viscoelasticity Spectra as a Result of Dynamic Mechanical Analysis.- 26. Morphologic and Functional Evaluation of the Human Corneal Endothelium.- Sessions IV and XII. Refractive Surgery.- 27. Corneal Tattooing to Treat Glare Symptoms following Radial Keratotomy.- 28. Refractive Results for the Nidek EC-5000 Excimer Laser Using a New Algorithmic Correction in 482 Eyes.- 29. Patient Motivation in PRK and Contact Lenses: Is PRK Only for Contact Lens Failures?.- 30. Excimer Laser for Correction of Myopic Astigmatism after Penetrating Keratoplasty.- 31. Phototherapeutic Keratectomy for the Treatment of Persistent Epithelial Defect.- 32. Corneal Endothelial Morphology and Barrier Function following Excimer Laser Photorefractive Keratectomy.- Session V. Molecular Biology, Cellular Biology, and Genetics.- 33. Wound Healing Modulators in Tear Fluid.- 34. Essential Role of a Protein Kinase C (PKC) Signal Transduction System in Corneal Epithelial Migration.- 35. Stromal-Epithelial Interactions in the Cornea.- 36. Regulatory Mechanism of Procollagenase Synthesis by Keratocytes.- 37. Molecular Mechanisms Controlling the Gene Expression Program for Corneal Repair.- Session VI. Contact Lenses.- 38. The Effect of Contact Lenses on the Conjunctiva.- Session VII. Microbial Keratitis Viral.- 39. The Biology and Pathology of Varicella Zoster Virus in the Ganglion.- Session VIII. Keratoconus.- 40. The Casefor Eye Rubbing as the Major Cause of Keratoconus.- 41. Long-Term Follow-up of Penetrating Keratoplasty for Keratoconus.- Session IX. Non-Microbial Keratitis and Immunology.- Session X. World Corneal Health.- 42. Childhood Keratitis: Epidemiological and Microbiological Study.- 43. Eosinophils in Ocular Inflammation: Histological and Ultrastructural Characteristics of Onchercercal Keratitis.- 44. Microbial Contamination of Donor Eyes.- 45. Severe Corneal Ulcerations and Vitamin A Deficiency: A Case Series.- 46. Corneal and Conjunctival Intraepithelial Neoplasia: A Clinical and Histopathological Analysis.- Session XI Microbial Keratitis Non-Viral.- 47. Medical and Surgical Treatment of Fungal Keratitis.- 48. Axial Myopia in Keratitis Phlyctaenulosa Caused by Form Deprivation Myopia.