Advances in Membrane Proteins

This book reviews recent advances regarding the biochemical and biophysical properties of membrane proteins and their applications in biomedicine. Divided into two thematic parts, this second volume addresses proteins' formation, signaling and malfunctions. It covers a number of important membrane proteins including receptors, cell adhesion molecules, single-transmembrane proteins and viral membrane proteins, and discusses their structures, functions, related diseases, and roles in drug discovery in detail.

In turn, the book elucidates the lifecycle of membrane proteins, including their synthesis and facilitated folding process, as well as QC procedures for their production. Additional topics include fundamental concepts, the latest findings, and critical puzzles yet to be solved. Given its scope, the book will appeal to a broad readership in the field of membrane structural and functional biology. Junior scientists can use it as an introduction to the field, while advanced scientists will find a broader view of the field beyond their area of specialization.

Summarizes the latest studies on biochemical and biophysical property of membrane proteins as well as their applications in biomedicine. Covers interesting topics on fundamental concepts, latest progress and critical puzzles yet to be solved Describes their structures, functions, related diseases as well as their roles in drug discovery

Autorentext
Dr. Yu Cao is a Professor at the Department of Orthopaedics and Institute of Precision Medicine, Shanghai Ninth People's Hospital, Shanghai and Jiao Tong University School of Medicine, Shanghai, China.

Inhalt

1. Cell adhesion molecules and development.- 2. Receptors and signal transduction.- 3. Single-transmembrane proteins and antibody drugs.- 4. Viral membrane proteins.- 5. Biosynthesis and folding of oily peptide chains.- 6. Quality control in producing membrane proteins.