Advances in Translational Neuroscience of Eye Movement Disorders

A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience. A rare collection with contributions from basic neuroscientists, neurologists, and ophthalmologists. Includes dedicated chapters on mathematical models, pharmacotherapy, neuromodulation, motion perception, visual influence on eye movement, physiology of strabismus, and microsaccades. This book is dedicated to David Robinson - one of the pioneers of contemporary ocular motor and vestibular neuroscience.

Includes a chapter on the effects of neuromodulation on eye movements Contributions from neuroscientists, neurologists, and ophthalmologists Diverse content from a coalition of world experts

Klappentext

1. The studies of eye movements - past, present, and future (David Zee, MD - Johns Hopkins, USA).-2. Computational models of saccades (Lance Optican, PhD - NIH, USA).-3. Microsaccades - cognitive, motor, sensory, or bit of all three? (Susana Martinez-Conde,PhD - SUNY Upstate, USA).-4. Neurophysiology of strabismus in macaque models (Vallabh Das, PhD - University of Houston, USA).-5. Translational neuroscience of slow saccades (Janet Rucker,MD - NYU, USA).-6. Role of visual system in the pathogenesis of eye movement disorders (Matthew Thurtell,MD - University of Iowa, USA).-7. Opsoclonus and ocular flutter - molecules, models, and medicines (Aasef Shaikh,MD,PhD - Case Western Reserve, USA).-8. Distinctive properties of microsaccades in visual and motor disorders (Jorge Otero-Millan,PhD - Johns Hopkins, USA).-9. The influence of deep brain stimulation on eye movements (Chrystalina Antoniades, University of Oxfor d, UK).-10. Inferior olive and cerebellum in motor learning of saccadic eye movements. (Aaron Wong,PhD - Johns Hopkins,USA).-11. Acquired pendular nystagmus (Aasef Shaikh,MD,PhD - Case Western Reserve University, USA).-12. What causes vertical nystagmus - cerebellum, brainstem, or both? (Dominic Straumann,MD - Zurich University, USA).-13. Eye movements in multiple sclerosis are diagnostic and therapeutic biomarkers (Alessandro Serra,MD,PhD - Case Western Reserve University, USA).-14. Disorders of eye movements in the epileptic patient (Aasef Shaikh,MD,PhD - Case Western Reserve University, USA).-15. Saccades in spinocerebellar ataxia (Alessandra Rufa,MD - University of Siena, Italy).-16. Ocular motor apraxia (Caroline Tilikete, MD,PhD - University of Lyon, France).-17. Vestibular perception - bench to bedside (Barry Seemungal, FRCP,PhD - Imperial College, UK).-18. Pharmacotherapy of vestibular and ocular motor disorders (Michael Strupp,MD - Ludwig Maxmillian, Germany).-19. Oculography in the emergency room - the "ECG" for acute vestibular syndrome. (David Newman-Toker,MD,PhD - Johns Hopkins, USA).-20. Updates on vestibular rehabilitation (Michael Schubert, PhD,PT - Johns Hopkins, USA).-21. The central mechanism of strabismus (Jonathan Horton,MD,PhD - Univ California San Francisco, USA).-22. Strabismus - the role of orbit and orbital muscles. (Joseph Demer,MD,PhD - Univ California Los Angeles, USA).-23. Pattern strabismus - where does the brain's role end and muscle's begin? (Fatema Ghasia,MD - Cleveland Clinic, USA).-24. Latent nystagmus - clinical implications of animal models (Lawrence Tychsen,MD - Washington University, USA).-25. Congenital nystagmus. (Irene Gottlob,MD - Leicester Royal Infirmary, UK).-26. Concluding remarks (Aasef Shaikh,MD,PhD - Case Western Reserve University,USA).

   Inhalt

   1. The studies of eye movements - past, present, and future (David Zee, MD Johns Hopkins, USA).-2. Computational models of saccades (Lance Optican, PhD NIH, USA).-3. Microsaccades - cognitive, motor, sensory, or bit of all three? (Susana Martinez-Conde,PhD SUNY Upstate, USA).-4. Neurophysiology of strabismus in macaque models (Vallabh Das, PhD University of Houston, USA).-5. Translational neuroscience of slow saccades (Janet Rucker,MD NYU, USA).-6. Role of visual system in the pathogenesis of eye movement disorders (Matthew Thurtell,MD University of Iowa, USA).-7. Opsoclonus and ocular flutter - molecules, models, and medicines (Aasef Shaikh,MD,PhD Case Western Reserve, USA).-8. Distinctive properties of microsaccades in visual and motor disorders (Jorge Otero-Millan,PhD Johns Hopkins, USA).-9. The influence of deep brain stimulation on eye movements (Chrystalina Antoniades, University of Oxfor
      d, UK).-10. Inferior olive and cerebellum in motor learning of saccadic eye movements. (Aaron Wong,PhD Johns Hopkins,USA).-11. Acquired pendular nystagmus (Aasef Shaikh,MD,PhD Case Western Reserve University, USA).-12. What causes vertical nystagmus - cerebellum, brainstem, or both? (Dominic Straumann,MD Zurich University, USA).-13. Eye movements in multiple sclerosis are diagnostic and therapeutic biomarkers (Alessandro Serra,MD,PhD Case Western Reserve University, USA).-14. Disorders of eye movements in the epileptic patient (Aasef Shaikh,MD,PhD Case Western Reserve University, USA).-15. Saccades in spinocerebellar ataxia (Alessandra Rufa,MD University of Siena, Italy).-16. Ocular motor apraxia (Caroline Tilikete, MD,PhD University of Lyon, France).-17. Vestibular perception bench to bedside (Barry Seemungal, FRCP,PhD Imperial College, UK).-18. Pharmacotherapy of vestibular and ocular motor disorders (Michael Strupp,MD Ludwig Maxmillian, Germany).-19. Oculography in the emergency room - the ECG for acute vestibular syndrome. (David Newman-Toker,MD,PhD Johns Hopkins, USA).-20. Updates on vestibular rehabilitation (Michael Schubert, PhD,PT Johns Hopkins, USA).-21. The central mechanism of strabismus (Jonathan Horton,MD,PhD Univ California San Francisco, USA).-22. Strabismus - the role of orbit and orbital muscles. (Joseph Demer,MD,PhD Univ California Los Angeles, USA).-23. Pattern strabismus - where does the brain's role end and muscle's begin? (Fatema Ghasia,MD Cleveland Clinic, USA).-24. Latent nystagmus - clinical implications of animal models (Lawrence Tychsen,MD Washington University, USA).-25. Congenital nystagmus. (Irene Gottlob,MD - Leicester Royal Infirmary, UK).-26. Concluding remarks (Aasef Shaikh,MD,PhD Case Western Reserve University,USA).