Cannabinoids in Neurologic and Mental Disease

The application of cannabis sativa for the treatment of neurologic and mental disease is expanding. Cannabinoids in Neurologic and Mental Disease collects and presents for the first time recent research involving the use of pharmacological cannabinoids for the treatment of neurodegenerative and neuroinflammatory disease. The neurologic application of cannabinoid therapy builds upon psychiatric and psychological use for the treatment of a variety of core mental disorders. This comprehensive reference on the known uses of cannabinoids will be useful for clinical neurologists, neuroscience and clinical neuroscience researchers, clinical psychologists and psychiatrists and the general medical community.

Autorentext
Liana Fattore is Senior Researcher at the Institute of Neuroscience, National Research Council of Italy (IN-CNR). She received a BSc in Biology in 1994, in Life Sciences in 1997 and a PhD in Neuroscience in 2003. From 2001 to 2002, she was Visiting Research Fellow at the Department of Experimental Psychology, University of Cambridge (UK). She currently leads preclinical research on the neurobiology of drug abuse and behavioral dependences at the Department of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, Italy. Her main fields of research focus primarily on addictive disorders, pathological dependences and behavioral dyscontrol, with special attention given to sex- and gender-dependent differences. Other research interests include neuropsychopharmacology, behavioral pharmacology, neurobiology of natural and drug reward, psychiatric disorders and comorbidity, new designer and internet drugs.Dr. Fattore has (co)authored over 80 scientific peer-reviewed publications (research articles, reviews, commentaries, perspective articles, book chapters); she serves as referee for more than 20 International Journals and as external and independent Expert Evaluator of Research Project Proposals for several European Agencies.She is Council Member of the Mediterranean Neuroscience Society (MNS) since 2012 and of the Italian Society of Neuroscience (SINS) since 2013. She heads the IN-CNR Laboratory of Behavioural Neuropharmacology in Cagliari that is home to young scientists from different backgrounds and academic levels wishing to experience a training period in behavioral neuroscience. She is strongly dedicated to increase awareness among high school students on the consequences of excessive drinking and substance abuse on health and brain functioning.

Inhalt
The ever expanding world of the endocannabinoids: a concise introduction - Fabiana Piscitelli and Vincenzo Di Marzo

PART I: ROLE OF THE ENDOCANNABINOIDS IN NEUROINFLAMMATORY AND NEURODEGENERATIVE DISORDERS
1. Cannabinoids for the treatment of Neuroinflammation - Maria L. de Ceballos

2. Endocannabinoids and Alzheimer's Disease - Steven George Fagan and Veronica A. Campbell
3. Cannabinoids in Parkinson's Disease - Eilís Dowd
4. Cannabinoids and Huntington's Disease - Cindy Casteels, Rawaha Ahmad, Matheiu Vandenbulcke, Wim Vandenberghe and Koen Van Laere
5. Endocannabinoids and Amyotrophic Lateral Sclerosis - Eva de Lago, Miguel Moreno-Martet, Francisco Espejo-Porras and Javier Fernández-Ruiz
6. Endocannabinoids and Epilepsy - Robert E. Blair, Laxmikant Deshpande and Robert J. DeLorenzo

7. Endocannabinoids and Migraine - Cristina Tassorelli

   PART II: ROLE OF THE ENDOCANNABINOIDS IN PSYCHOLOGICAL AND PSYCHIATRIC DISORDERS
   8. Cannabinoids and Schizophrenia - Cathrin Rohleder and F. Markus Leweke

8. Cannabinoids and Bipolar Disorder - Raphael J. Braga, Sherif Abdelmessih, Juliana Tseng and Anil Kumar Malhotra
9. Cannabinoids and Tourette syndrome - Kirsten R. Müller-Vahl
10. The Role of Endocannabinoid Function in Posttraumatic Stress Disorder: Modulating the Risk Phenotype and Rendering Effects of Trauma - Frances H. Gabbay, Kwang H. Choi, Gary Wynn and Robert J. Ursano
11. Cannabinoids and Drug Addiction - Maria Antonietta De Luca and Liana Fattore

12. Cannabinoids and appetite (dys)regulation (Obesity) - Claire M. Williams, Benjamin J. Whalley and Ciara McCabe

    PART III: ROLE OF THE ENDOCANNABINOIDS IN IMPULSIVE AND COMPULSIVE DISORDERS
    14. The cannabinoid system and impulsive behavior - Joost Wiskerke and Tommy Pattij

13. Cannabinoids and compulsive-obsessive disorder - Plinio C. Casarotto, Felipe V. Gomes and Francisco Silveira Guimarães
14. The endocannabinoid system: anorexia nervosa and binge eating disorder - Maria Scherma, Valentina Satta, Walter Fratta and Paola Fadda
15. The Endocannabinoid System and Trichotillomania: A Promising Target for Treatment? - Jon E. Grant, Brian L. Odlaug and Samuel R. Chamberlain
16. CONCLUSIONS: FUTURE PERSPECTIVES Cannabinoid CB2 receptor ligands and their therapeutic potential in mental diseases - Emmanuel S. Onaivi, Hiroki Ishiguro and Qing-Rong Liu