Congenital and Perinatal Infections

A concise clinical reference that facilitates the diagnosis of intrauterine and perinatally acquired infections was the goal in creating the Congenital and Perinatal Infections: A Concise Guide to Diagnosis. Information about the natural history, m- agement, and outcome of these infections is well detailed in many other sources and so has not been included. Rather, the focus of the book is diagnosis. The initial chapters provide general information about serological and nonserological assays that are used for the diagnosis of infections, and a chapter about the placenta includes details about histopathological findings that can be helpful with the diagnosis of congenital inf- tions. The remainder of the book is devoted to the diagnosis of specific congenital and/ or perinatal infections. As illustrated in the chapters about specific infections, the approach to diagnosis of a congenital or perinatally acquired infection in the neonate begins, when possible, with consideration and diagnosis of infection in the pregnant woman, knowledge of how the infection is transmitted, and the risk of that infection for the woman and her fetus or neonate. The possibility of congenital or perinatal infection in neonates is usually considered because of the diagnosis of, or concern about a s- cific infection in, a mother during pregnancy that can be transmitted to the neonate or because of clinical findings in the neonate at birth that suggest an infectious cause.

Includes supplementary material: sn.pub/extras

Klappentext
Although information about the natural history, management, and outcome of intrauterine and perinatally acquired infections is readily available, the busy clinician requires methods for quickly and easily determining the diagnosis of these infections, especially in a time of ever changing advances in diagnostic technology and the emergence of new infectious agents. In Congenital and Perinatal Infection: A Concise Guide to Diagnosis, a distinguished panel of pediatric and infectious disease specialists present in an easily accessible format all the information needed to diagnose a wide variety of infections in both the pregnant woman and the neonate. Organized by specific infection or related infections, the book provides pertinent information about the epidemiology of each infection in the pregnant woman and her neonate, as well as the risk of transmission to the fetus or neonate, the spectrum of clinical disease, and a recommended approach to the diagnosis of the infection in not only the mother, but also her neonate. The emphasis is on understanding what tests to order and how to interpret the results, with the approach to diagnosis in each chapter encompassing both the pregnant woman and her neonate. The book covers a wide range of micro-organisms that are both common and uncommon causes of congenital and perinatal infections, including the herpes simplex virus, HIV, toxoplasmosis, syphilis, CMV, tuberculosis, malaria, dengue, lymphocytic choriomeningtis virus, and parvovirus.
Up to date and user friendly, Congenital and Perinatal Infection: A Concise Guide to Diagnosis offers the busy clinician caring for pregnant women and/or their infants a practical guide to determining infection risks and which assays are the most appropriate to use for their diagnosis.

Inhalt
The Tools of Diagnosis.- Diagnostic Assays.- Nonserologic Assays for Detection of Bacteria and Other Nonviral Infections.- Diagnosis of Viral Infections by Viral Isolation and Identification or by Direct Detection.- Placental Histopathology.- Diagnosis of Specific Infections.- Herpes Simplex Virus.- Cytomegalovirus.- Epstein-Barr Virus.- Varicella-Zoster Virus.- Human Herpesviruses 6 and 7.- Human Herpesvirus 8.- Rubella.- Parvovirus B19.- Enteroviruses.- Human Immunodeficiency Virus Type 1.- Hepatitis Viruses.- Lymphocytic Choriomeningitis Virus.- Dengue Virus.- Syphilis.- Group B Streptococcus.- Listeria monocytogenes, Neisseria gonorrhoeae, and Other Bacteria.- Mycobacterium tuberculosis.- Toxoplasma gondii.- Chlamydia trachomatis.- Mycoplasma and Ureaplasma.- Candida.- Malaria.