Extrusion Bioprinting of Scaffolds for Tissue Engineering

This book introduces readers to the theory and practice of extrusion bioprinting of scaffolds for tissue engineering and modeling. The text emphasizes the fundamentals and practical applications of extrusion bioprinting for scaffold fabrication, in a manner particularly suitable for those (including both undergraduate and graduate students) who wish to master the subject matter and apply it to real tissue engineering. Readers will learn how to design, fabricate, and characterize tissue scaffolds to be created by extrusion bioprinting technologies. This book:

• Covers tissue engineering and various scaffold fabrication techniques
• Presents the general requirements imposed on scaffolds and the scaffold design process
• Discusses the preparation and characterization of biomaterials and bioink for extrusion bioprinting
• Educates readers regarding how to bioprint and characterize scaffolds with living cells for tissue engineering and modeling
• Introduces the common methods/ techniques used to measure and characterize the mechanical properties of native tissues and scaffolds
• Discusses various approaches to create vascular networks within tissue scaffolds to facilitate their functions
• Introduces the concept of controlled release and the common strategies for regulating biomolecules in tissue engineering and printed scaffolds

• Includes many case studies of bioprinting and characterizing scaffolds for tissue engineering and modeling, to reflect the recent advances in the field of bioprinting

  Provides a comprehensive introduction to extrusion bio-printing technology Discusses advances in creating vascular networks and controlled-release strategies within printed scaffolds Educates readers to design, bioprint, and characterize scaffolds for tissue engineering and modeling

  Autorentext

Dr. Chen is a Professor with the Department of Mechanical Engineering and Division of Biomedical Engineering at the University of Saskatchewan (USask), Canada. Dr. Chen is a Fellow of the Canadian Academy of Engineering (CAE), Engineering Institute of Canada (EIC), Canadian Society for Mechanical Engineering (CSME), and American Society of Mechanical Engineers (ASME). He is also the recipient of several awards in recognition of his research excellence, including the 2016 Achievement Award from Saskatchewan Health Research Foundation.

Dr. Chen received his Ph.D. degree from the USask in 2002 and then worked on his Post-Doctorate with Queen's University, Canada. In 2003 he was appointed as an Assistant Professor with the USask, where he was promoted to an Associate Professor and a full Professor in 2007 and 2010, respectively. Dr. Chen's research interests mainly include bioprinting and tissue engineering. His research has been supporting by the Natural Sciences and Engineering Research Council (NSERC) of Canada, Canadian Institutes of Health Research (CIHR), Canada Foundation for Innovation (CFI), and Saskatchewan Health Research Foundation (SHRF). He teaches undergraduate and graduate courses in the areas of biomedical engineering and mechanical engineering.

Inhalt

Extrusion Bioprinting of Scaffolds: an Introduction.- Scaffold Design for Bioprinting.- Biomaterials for Bioprinting.- Mechanical Properties of Native Tissues and Scaffolds.- Preparation of Scaffold Solutions and Characterization of Their Flow-Behavior.- Extrusion Bioprinting of Scaffolds.- Bioprinting Vascular Networks in Scaffolds.

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