Models and time series analysis for anaesthesia

Nowadays, physiological monitoring is imperative for
the safety of medical operations. However, systems
which monitor the depth of anaesthesia are still far
from reliable, such that still some patients may
experience the trauma of remaining conscious under
general anaesthesia during surgery. To tackle this
problem, an interdisciplinary project "Brain
Respiration and Cardiac Causalities in Anaesthesia
(BRACCIA)" was created. The main objective of this
project was to establish how the couplings between
the cardiac, respiratory and cortical oscillations
change in anaesthesia. Under the framework of this
project, our objectives were: 1) The detection of
the deep-light change of anaesthesia from
experimental recordings on rats, and furthermore,
the investigation of the interdependencies among
three physiological activities, namely, the cardiac
activity (H), respiration (R) and cortical
activities (B) from experimental recordings of rats
and humans, for each state of the depth of
anaesthesia. 2) The modelling of the slow brain
waves, and to consider the effect of anaesthesia on
this model. This monograph explains in
detail our methods and obtained results.

Autorentext

She was born in Miyazaki (Japan) in 1978. She received the B. Sc. and the M. Sc. degrees in electrical and electronic engineering from Sophia University, Tokyo, Japan. And then, she obtained the Ph. D. degree in computer and communication sciences from Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland in 2008.

Klappentext

Nowadays, physiological monitoring is imperative for the safety of medical operations. However, systems which monitor the depth of anaesthesia are still far from reliable, such that still some patients may experience the trauma of remaining conscious under general anaesthesia during surgery. To tackle this problem, an interdisciplinary project "Brain Respiration and Cardiac Causalities in Anaesthesia (BRACCIA)" was created. The main objective of this project was to establish how the couplings between the cardiac, respiratory and cortical oscillations change in anaesthesia. Under the framework of this project, our objectives were: 1) The detection of the deep-light change of anaesthesia from experimental recordings on rats, and furthermore, the investigation of the interdependencies among three physiological activities, namely, the cardiac activity (H), respiration (R) and cortical activities (B) from experimental recordings of rats and humans, for each state of the depth of anaesthesia. 2) The modelling of the slow brain waves, and to consider the effect of anaesthesia on this model. This monograph explains in detail our methods and obtained results.