Neurotropic Viral Infections

This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities).

Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into two separate volumes. Volume 1, Neurotropic RNA Viruses, includes 14 chapters on RNA viruses that cause human disease of the central nervous system ranging from Bornavirus to polio to West Nile.

Volume 2, Neurotropic Retroviruses, DNA Viruses, Immunity and Transmission, includes 15 chapters divided into two parts. Part 1 includes 7 chapters on retroviruses and DNA viruses that cause human disease of the central nervous system ranging from HIV to varicella zoster virus. Part 2 includes chapters on transmission of these viruses by transplantation, bites by bats and insects, clinical management of the infections, and beneficial uses of attenuated viruses.

Neurotropic Viral Infections is a unique resource, bridging basic, clinical, and translational approaches.

Unique in bridging basic, clinical, and translational approaches Explores the ways in which viruses cause disease, as well as how the immune system reacts? Addresses diagnostic/discovery techniques for identifying new and emerging infections

Autorentext
Carol Shoshkes Reiss is a professor in the department of biology at New York University.

Inhalt

Part 1.- Retroviruses, DNA Viruses and Prions.- The pathogenesis of HTLV-1-associated myelopathy/tropical spastic paraparesis.- HIV.- Molecular biology of JC virus and the human demyelinating disease, progressive multifocal leukoencephalopathy.- The Herpes Simplex Viruses.- The Pathogenesis of Varicella-Zoster Virus Neurotropism and Infection.- Virus Induced Demyelination: The Case for Virus(es) in Multiple Sclerosis.- Transmissible Spongiform Encephalopathies.- Part 2.- Immunity, Diagnosis, Vectors and Beneficial Uses of Neurotropic Viruses.- Innate Immunity in Viral Encephalitis.- Neuroendocrine-immune interactions in neurotropic viral infections.- Clinical Management of Viral Encephalitis.- Influences of Arthropod Vectors on Encephalitic Arboviruses.- The Role of Bats as Reservoir Hosts of Emerging Neuroviruses.- Transmission of neurotropic viruses by transplantation.- Viral Oncolysis of Glioblastoma.- Viral Gene Therapy for Central Nervous System Diseases.