Occupational Cancers

This up-to-date review of the literature on the epidemiology and pathology of work-related cancers also includes sensitive diagnostic questionnaires and data on the risk ratios of differing cancers in relation to a variety of occupations and lifestyle factors.

This book is a comprehensive guide to occupational factors of malignant diseases. It discusses potentially work-related malignancies, in the context of exposure assessment, specific clinical and pathological features of occupational cancer and biomarkers of exposure and disease. Epidemiological data about risk ratios of the cancer in question are reviewed for various occupations and with exposure to specific carcinogens, carcinogenic mechanisms, host susceptibility factors (genetic and other) and other environmental and life-style risk factors. Aspects such as surveillance of workers exposed to carcinogens and strategies for prevention of occupational cancer are also discussed.

Occupational Cancers is aimed at oncologists, pathologists, residents in training, clinical researchers, clinicians in occupational health, epidemiologists, pulmonologists, lawyers and public health officials.

Multidisciplinary view of occupational factors of cancer for readers with different backgrounds Covers epidemiology, clinical features and pathology, as well as molecular carcinogenic mechanisms and biomarkers Emphasizes prevention at an individual level as well as in populations and familiarizes readers with preventive strategies

Autorentext
Paolo Boffetta, MD, MPHBluhdorn Professor of International Community MedicineDirector, Institute for Translational EpidemiologyAssociate Director for Population Sciences, Tisch Cancer InstituteIcahn School of Medicine at Mount SinaiOne Gustave L. Levy PlaceNew York, NY, USASisko Anttila MD, PhDHelsinki University Central Hospital, Hospital District of Helsinki and Uusimaa, Laboratory Services, HUSLAB, andFinnish Institute of Occupational Health, Helsinki, Finland.

Inhalt

Historical Overview of Occupational Cancer Research.- Genetics and Gene-Environment Interactions.- Mechanisms of Environmental and Occupational Carcinogenesis.- Cancer of the Oral Cavity, Pharynx and Nasopharynx.- Pancreatic Cancer.- Cancers of the Intestine, Liver and Biliary Tract.- Sinonasal Cancer.- Laryngeal Cancer.- Lung cancer (exposure assessment, pathology, epidemiology).- Lung Cancer: Mechanisms of Carcinogenesis.- Lung Cancer: Genetic Susceptibility.- Lung Cancer: Molecular Markers.- Malignant Mesothelioma: Epidemiology.- Malignant Mesothelioma: Clinical and Imaging Findings.- Malignant Mesothelioma: Asbestos Exposure.- Malignant Mesothelioma: Pathology.- Malignant Mesothelioma: Mechanism of Carcinogenesis.- Malignant Mesothelioma: Genetic Susceptibility.- Malignant Mesothelioma: Molecular Markers.- Neoplasm of Soft Tissues.- Malignant Neoplasms of the Skin.- Breast Cancer.- Malignant Tumors of the Female Reproductive System.- Malignant Tumors of the Male Reproductive System.- Kidney Cancer.- Bladder Cancer.- Malignant Tumors of the Central Nervous System.- Lymphohematopoietic Malignancies.- Occupational Cancer Burden.- Occupational Carcinogens and Cancer in Children.- Strategies for Primary Prevention of Occupational Cancer.- Screening for Occupational Cancer.- Role of Registers in Occupational Cancer Control.- Appendix I Questionnaire on Exposure to Asbestos.