Population Neuroscience

This book breaks new ground in its effort to interlink genetics, epidemiology and cognitive neuroscience. It provides practitioners with the tools and knowledge base to collaborate on large-scale imaging studies of the developing, mature and aging brain.

Is Newton's brain different from Rembrandt's? Does a mother's diet during pregnancy impact brain growth? Do adolescent peers leave a signature in the social brain? Does the way we live in our middle years affect how our brains age? To answer these and many other questions, we can now turn to population neuroscience. Population neuroscience endeavors to identify environmental and genetic factors that shape the function and structure of the human brain; it uses the tools and knowledge of genetics (and the omics sciences), epidemiology and neuroscience. This text attempts to provide a bridge spanning these three disciplines so that their practitioners can communicate easily with each other when working together on large-scale imaging studies of the developing, mature and aging brain.By understanding the processes driving variations in brain function and structure across individuals, we will also be able to predict an individual's risk of (or resilience against) developing a brain disorder. In the long term, the hope is that population neuroscience will lay the foundation for personalized preventive medicine and, in turn, reduce the burden associated with complex, chronic disorders of brain and body.

First book-length treatment of population neuroscience Breaks new ground in its effort to interlink genetics, epidemiology and cognitive neuroscience Provides the practitioners of these three fields with the tools and knowledge base to collaborate on large-scale imaging studies of the developing, mature and aging brain Includes supplementary material: sn.pub/extras

Inhalt
Terms and Concepts.- History of the Key Disciplines.- Enviromics.- Genomics.- Epigenomics.- Molecular Phenomics.- Systems Phenomics.- Cohorts.- Challenges.- Personalized Preventive Medicine.