The Role of Sphingolipids in Cancer Development and Therapy: Volume 117

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "The Role of Sphingolipids in Cancer Development and Therapy"

Klappentext

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "The Role of Sphingolipids in Cancer Development and Therapy." With outstanding and original reviews, this volume covers topics such as sphingosine kinase, platforms for the design of sphingolipid derived anticancer agents, and functions of ceramide on cancer cell death and proliferation.

Zusammenfassung
Provides information on the field of cancer research.

Inhalt

1. Therapeutic potential of targeting SK1 in human cancers
2. Natural products as platforms for the design of sphingolipid derived anticancer agents
3. Hypoxia, therapeutic resistance and sphingosine 1-phosphate
4. Use of acid sphingomyelinase for cancer therapy
5. Diverse functions of ceramide on cancer cell death and proliferation
6. Sphingosine kinase and cancer
7. Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance
8. Interdiction of sphingolipid metabolism to improve standard of care cancer therapies