Tumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on non-hematopoietic cells within the tumor microenvironment.Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include fibroblasts, adipocytes, mesenchymal stem cells, stellate cells, and more.

Taken alongside its companion volumes, Tumor Microenvironment: Non-Hematopoietic Cells updates us on what we know about the different aspects of the tumor microenvironment as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists focused in the tumor microenvironment and how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

All of the chapter authors are renowned international experts in the cancer biology field in specific subfields that will be the focus of their chapters.

Provides a thorough review of fibroblasts, pericytes, endothelial cells, adipocytes, and nerves in the tumor microenvironment Covers the non-hematopoietic constituents of tumor microenvironment for an audience of advanced cell biology and cancer biology students Editor and contributors represent international perspective and key leaders' expertise

Autorentext
Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Inhalt

Adipocytes in the tumour microenvironment.- Fibroblasts in the tumor microenvironment.- Mesenchymal stem cells in the tumor microenvironment.- Hepatic stellate cells in liver tumor.- Pancreatic stellate cells: The key orchestrator of the pancreatic tumor microenvironment.- Endothelial cells in the tumor microenvironment.- Lymphatic endothelial cell progenitors in the tumor microenvironment.- Oligodendrocyte progenitors in the tumor microenvironment.- Index.