A Combinatorial Approach in Metal Cytotoxic Mechanisms

A combinatorial approach in metal cytotoxic mechanisms condenses the diffuse literature on metal toxicology into an accessible and readable text. It introduces fundamental concepts in mechanistic toxicology and use a functionomic approach to understand the heavy metals cytotoxic mechanism, e.g., the effects of inhibitors or substrates of metabolizing enzyme/transporting pathway and other cellular vital pathways on the loss of cell viability and oxidative stress markers induced by the heavy metals. A combinatorial approach in metal cytotoxic mechanisms will be invaluable for students and teachers of toxicology and also for those such as environmental scientists, biologists, chemists / chemical engineers or even legislators working in related area. For these groups the book provides a comprehensive and practical introduction to the whole subject.

Autorentext

Dr. Jalal pourahmad graduated as Doctor of Pharmacy in 1988 From Mashhad University, Iran and as Ph.D. in Toxicology in 2001 from University of Toronto, Canada. He is currently working as a Full Professor in Shaheed Beheshti University of Medical Sciences, Tehran, Iran. He has so far published more than 50 scientific papers in Farsi and English.