Adenosine Versus Theophylline Toxicity

Adenosine has been implicated in the spontaneous and abrupt arrest of seizures (Dragunow, 1986). The anticonvulsant action of adenosine and its analogs has been observed in several different studies. adenosine and its analogs protect against audiogenic, chemically-induced and kindled seizures. Theophylline-induced convulsions may be related to a cerebral vasoconstriction or to an antagonistic effect on the central adenosine receptors.

Autorentext

Dr.Romany Helmy Thabet, Assistant Professor of pharmacology, Faculty of Medicine, Northern Borders University, Saudi Arabia. So interested in immunopharmacology and pharmacogenomics research. My Latest Publications is titled''Genetic variants in 6-mercaptopurine pathway as potential factors of hematological toxicity in acute lymphoblastic leukemia