Advances in Antiviral Drug Design

Zusammenfassung Covers the progress made in the field of antiviral drug research and highlights five specific directions that have opened fresh avenues for the treatment of virus infections including HIV! HBV and influenza virus.

Inhalt
List of Contributors. Preface. From D- to L-nucleoside analogs as antiviral agents. Orally bioavailable acyclic nucleoside phosphonate prodrugs: adefovir dipivoxil and BIS(POC)PMPA. HEPT: from an investigation of lithiation of nucleosides towards a rational design of non-nucleoside reverse transcriptase inhibitors of HIV-1). Sialidase inhibitors as anti-influenza drugs. Bicyclam derivatives as HIV inhibitors. Index.