Advances in Immunology: Volume 84

Informationen zum Autor Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School. Klappentext Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Interactions between NK Cells and B Lymphocytes Multitasking of helix-loop-helix proteins in lymphopoiesis* The pathogenesis of Diabetes in the NOD Mouse Inhaltsverzeichnis Interactions between NK Cells and B Lymphocytes Multitasking of helix-loop-helix proteins in lymphopoiesis Customized antigens for desensitizing allergic patients The immune response atainst dying tumor cells HMGB1 in the Immunology of Sepsis (not Spetic Shock) and Arthritis Selection of the T cell repertoire: Receptor-controlled checkpoints in T cell development The pathogenesis of Diabetes in the NOD Mouse...

Autorentext
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Klappentext

Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

• Interactions between NK Cells and B Lymphocytes Multitasking of helix-loop-helix proteins in lymphopoiesis The pathogenesis of Diabetes in the NOD Mouse

  Inhalt

  Interactions between NK Cells and B Lymphocytes
  Multitasking of helix-loop-helix proteins in lymphopoiesis
  Customized antigens for desensitizing allergic patients
  The immune response atainst dying tumor cells
  HMGB1 in the Immunology of Sepsis (not Spetic Shock) and Arthritis
  Selection of the T cell repertoire: Receptor-controlled checkpoints in T cell development
  The pathogenesis of Diabetes in the NOD Mouse