Advances in Nitrate Therapy

The book describes all aspects of nitrate therapy. The indication, effectiveness, and contraindication are discussed systematically for each drug.

Inhalt
A. Introduction and Mechanism.- 1. Introduction.- 2. The Mechanism of Action of Nitrates at the Cellular Level.- B. Indications.- 3. Stable Angina Pectoris.- 4. The Mechanism of Action of Nitrates in Angina Pectoris.- 5. Nitrates Compared and Combined with Other Antianginal Drugs.- 6. Unstable Angina Pectoris.- 7. Long-Term Use of Nitrates in Angina Pectoris.- 8. Silent Ischemia.- 9. Acute Myocardial Infarction.- 10. Congestive Heart Failure.- 11. Congestive Heart Failure and Valvular Diseases.- 12. Long-Term Nitrate Therapy in Congestive Heart Failure.- 13. Nitrates Combined and Compared with Other Drugs in Congestive Heart Failure.- 14. Systemic Hypertension, Arrhythmias and Cardiac Surgery.- 15. Pulmonary, Abdominal, and Peripheral Vascular Effects.- 16. Non-Cardiovascular Indications for Nitrates.- 17. Nitrates in Children and the Elderly.- C. Nitrate Formulations and Routes of Administration.- 18. Sublingual Tablets and Oral Spray.- 19. Intravenous Administration of Nitrates.- 20. Intracoronary Administration of Nitrates.- 21. Oral Administration of Nitrates.- 22. Mononitrates.- 23. Transdermal Administration of Nitrates.- 24. Buccal Nitroglycerin.- D. Pharmacology.- 25. Clinical Pharmacology.- 26. Side Effects and Drug Interactions.- 27. Dosage and Administration.- E. Conclusions.- References.