Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation

Inhalt

1. Smooth Muscle Myosin: Molecule Conformation, Filament Assembly and Associated Regulatory Enzymes.- 2. Actin and Thin-Filament-Associated Proteins in Smooth Muscle.- 3. Current Concepts on Mechanisms of Force Generation in Airways Smooth Muscle.- 4. Phosphoinositidase C, Inositol Polyphosphates and Force Generation of Airways Smooth Muscle.- 5. The Intracellular Calcium Store in Airways Smooth Muscle.- 6. Current Concepts on Mechanisms of Force Maintenance in Airways Smooth Muscle.- 7. Diglyceride, Protein Kinase C and Force Maintenance of Airways Smooth Muscle.- 8. Sources of Activator Calcium for Force Generation and Maintenance of Airways Smooth Muscle.- 9. G-Proteins in Airways Smooth Muscle.- 10. Cyclic AMP and the Control of Airways Smooth Muscle Tone.- 11. Myosin Dephosphorylation as a Mechanism of Relaxation of Airways Smooth Muscle.- 12. Cyclic GMP and the Control of Airways Smooth Muscle Tone.- 13. Cyclic Nucleotide Phosphodiesterases in Airways Smooth Muscle.- 14. Modulation of Agonist-Stimulated Phosphoinositide Turnover in Airways Smooth Muscle by Cyclic Nucleotide-Dependent and Independent Mechanisms.- 15. Airways Smooth Muscle Cells in Culture.