American Trypanosomiasis Chagas Disease

American Trypanosomiasis, Chagas Disease: One Hundred Years of Research, Second Edition, provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease, the host, the insect vectors, and the causative parasite.

In addition, new insights on the molecular biology and diagnostics of Chagas diseases, the persistence of infections in the host, and the interaction of the parasite and host metabolism are now included in this new and updated edition.

Autorentext
Jenny Telleria, the initiator of the present book, got her PhD degree in the area of population genetics and parasitology at the University of Montpellier, France. She started her work in the area of parasitology in 1990 as university teacher assistant. Since then she has focused her research on the three components of Chagas disease, namely: the host, the vector and mainly the parasite (Trypanosoma cruzi).She has worked in several countries in Latin America and Europe, (Bolivia, Brazil, Venezuela, Belgium and France). She has presently a permanent position of Research Engineer at the French Institut de recherche pour le développement” (IRD) and she has been Dr Michel Tibayrenc's collaborator for more than 17 years.At present, she works at the Center of Research in health of Latin America "CISeAL", Quito-Nayon, Ecuador. Recent research deals with experimental evolution of T. cruzi, more specifically the parasite's gene expression surveyed by proteomics analysis.Dr. Michel Tibayrenc has worked on the evolution of infectious diseases for more than 45 years. He is a director of research emeritus at the French Institut de Recherche pour le Developpement (IRD) and the founder and editor-in-chief emeritus of the Elsevier journal Infection, Genetics and Evolution. From 1996-2021 he was the founder and principal organizer of Elsevier's international MEEGID congress (Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases). He has held professional appointments in France, Algeria, French Guiana, Bolivia, Thailand, and the United States; is the cofounder of the Bolivian Society of Human Genetics; and is a fellow of the American Association for the Advancement of Science.

Inhalt

1. General Aspects2. Insect Vectors3. Non-Human Mammalian Hosts4. The Causative Agent: Trypanosoma cruzi5. Modes of Transmission6. Immunology: Host-Parasite Interaction7. Pathology, Diagnosis and Treatment