Amisulpride
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High Quality Content by WIKIPEDIA articles! Amisulpride (sold as Solian), is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. In small doses it is also used to treat depression. It was introduced by Sanofi-Aventis in the 1990s. Amisulpride functions primarily as a D2 and D3 receptor antagonist. It has high affinity for these receptors with dissociation constants of 2.8 nM and 3.2 nM, respectively. Although standard doses in the 400 to 1200 mg a day range used to treat psychosis inhibit dopaminergic neurotransmission, low doses in the 50 to 200 mg range preferentially block inhibitory pre-synaptic autoreceptors. This results in a facilitation of dopamine activity, and for this reason, low dose amisulpride has also been used to treat clinical depression.
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GarantieWeitere Informationen
- Allgemeine Informationen
- GTIN 09786131694059
- Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
- Genre Psychologie
- Größe H8mm x B220mm x T150mm
- EAN 9786131694059
- Format Fachbuch
- Titel Amisulpride
- Gewicht 215g
- Herausgeber Alphascript Publishing
- Anzahl Seiten 132
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