ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ASSAY

We developed methods for determination and validation of carvedilol in bulk and pharmaceutical dosage forms by RP- HPLC method with some improvements than the existing method.The analytical procedure described for assay was specific, linear, precise, accurate, and system suitable for determination of carvedilol in bulk and pharmaceutical dosage forms.The observations of the validation parameters such as accuracy, precision, specificity, linearity, shows that the developed methods can be employed for routine analysis of bulk and tablets form of carvedilol. The result obtained from the validation parameters met the ICH and USP requirement.

Autorentext

Ho conseguito un master in chimica farmaceutica presso l'università RGPV (M.P.), un diploma di specializzazione in chimica farmaceutica (medaglia d'oro) presso l'università Dayalbagh di Agra e un diploma di laurea in chimica farmaceutica presso l'UPTU (U.P.).Ho 4 anni di esperienza industriale nel reparto QC e attualmente lavoro come professore aggiunto presso il Nova College of Pharmacy di Lucknow.