Animal Models of Human Disease: Volume 100

Klappentext Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. This volume reviews the latest research and developments in this field. Discusses new discoveries, approaches, and ideas Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields PRAISE FOR THE SERIES "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal Zusammenfassung Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining various therapies. This title reviews the research and developments in this field. It discusses different discoveries! approaches! and ideas. It is suitable for researchers involved in molecular biology and related fields. Inhaltsverzeichnis 1. Modelling cancers in Drosophila Dr. Lucas Waltzer 2. Modeling human prostate cancer in mice Dr. Fen Wang 3. The Drosophila heart: a model system for the genetics of cardiac disease and senescence Dr. Robert Wessells 4. Dissection of cardiovascular development and disease pathways in zebrafish John D. Mably 5. Transgenic mouse models of human cardiovascular and blood diseases Dr. Simon J. Conway 6. 800 Facets of Retinal Degeneration Dr. Andrew C. Zelhof 7. Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio Dr. Jeffrey M Gross 8. Mouse models of retinal disease Dr. Paul N. Baird 9. Eating on the Fly: Studying Metabolic Diseases in Drosophila melanogaster Dr David Tree 10. Mouse models of selected inborn errors of metabolism William J. Craigen 11. Modeling disoders of mitochondrial fatty acid metabolism in the mouse Dr. Eric Goetzman 12. Watching Worms Whither: Modeling Neurodegeneration in C. elegans Dr. Benjamin Wolozin 13. Demise of the Flies?: Why Drosophila Models Still Matter George R. Jackson 14. Utility of zebrafish to late-onset neurology: A developmental model coming of age W. Ted Allison 15. Genetic Mouse Models of Neurodegenerative Diseases Darren J. Moore ...

Inhalt

1. Modelling cancers in Drosophila

   Dr. Lucas Waltzer

   2. Modeling human prostate cancer in mice

   Dr. Fen Wang

   3. The Drosophila heart: a model system for the genetics of cardiac disease and senescence

   Dr. Robert Wessells

   4. Dissection of cardiovascular development and disease pathways in zebrafish

   John D. Mably

   5. Transgenic mouse models of human cardiovascular and blood diseases

   Dr. Simon J. Conway

   6. 800 Facets of Retinal Degeneration

   Dr. Andrew C. Zelhof

   7. Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio

   Dr. Jeffrey M Gross

   8. Mouse models of retinal disease

   Dr. Paul N. Baird

   9. Eating on the Fly: Studying Metabolic Diseases in Drosophila melanogaster

   Dr David Tree

   10. Mouse models of selected inborn errors of metabolism

   William J. Craigen

   11. Modeling disoders of mitochondrial fatty acid metabolism in the mouse

   Dr. Eric Goetzman

   12. Watching Worms Whither: Modeling Neurodegeneration in C. elegans

   Dr. Benjamin Wolozin

   13. Demise of the Flies?: Why Drosophila Models Still Matter

   George R. Jackson

   14. Utility of zebrafish to late-onset neurology: A developmental model coming of age

   W. Ted Allison

   15. Genetic Mouse Models of Neurodegenerative Diseases

   Darren J. Moore