Antimicrobial Coatings and Modifications on Medical Devices

Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance on devices and products. Antimicrobial Coatings and Modifications targets reduction of microbial accumulation on biomedical and industrial materials through changing interfacial characteristics. Applying a viable antimicrobial coating or modification to resist alarming threats is a highly demanding requirement for many medical and engineering applications. Many contemporary books in the area of antimicrobial solution focus on applying antimicrobial agents or materials that can kill bacteria. The volume pays more attention to eliminating bacterial contamination and biofilm formation through surface characteristics with minimized bacterial resistance and environmental impact.

Provides insight into antimicrobial design from the perspective of bacteria-material interactions; Elucidates the fundamentals of obstructing bacteria/biofilm formation based on surface characteristics; Discusses state-of-the-art applications of coatings and modifications on various devices and substrates, providing applicable and economic avenues for anti-microbial solutions; Presents solutions to avoid overuse of antimicrobial agents that cause environmental pollution and antibiotic resistance; Covers regulatory science challenges on antimicrobial medical devices and environmentally benign antimicrobial coatings crucial for product development. Includes supplementary material: sn.pub/extras Includes supplementary material: sn.pub/extras

Autorentext
Dr. Zheng Zhang is Principle Scientists and one of the founding researchers at Semprus BioScience, a biotechnology R&D firm established in the Langer Laboratory at MIT.

Inhalt
Chapter 1. Anti-Microbial Technologies on Critical Care Implants.- Chapter 2 Antimicrobial and Anti-biofilm Medical Devices - Public Health and Regulatory Science Challenges.- Chapter 3 Characterization of bacterial adhesion and biofilm formation.- Chapter 4 Molecular approaches for studying biofilms: techniques, challenges and future prospects.- Chapter 5 Implantable medical devices modified with antimicrobial substances.- Chapter 6 Anti-antimicrobial approaches to device-based infections.- Chapter 7 Releasing antimicrobial agents from porous materials.- Chapter 8 Anti-fouling medical coatings.- Chapter 9 Exploring the potential of light to prevent and treat microbial biofilms in medical and food applications.- Chapter 10 Light-triggered anti-infective surface.