Artemisinin and Nitric Oxide

This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted Molecule of the Year by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology. The book explains why we should maintain a steady-state NO level that is derived from neuronal or epithelial NO synthase, and avoid the extremely high NO level resulting from inducible NO synthase. The book offers a valuable resource for medical chemists, clinicians, biologists and all those interested in health and disease.

Introduces a uniform nitric oxide threshold theory in disease and health Explains why low-level nitric oxide is beneficial and high-level nitric oxide is harmful for health Guides people to understand the potential of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging Prospects to reveal the systemic and chronic low-grade inflammation as a common initiator of dermentia, obesity, and cancer Includes supplementary material: sn.pub/extras

Inhalt
Background.- Biological Features of NO and Pharmacological Principles of ART.- ART for Antitumor.- ART for Antibacterial Infection.- ART for Anti-inflammation.- ART for Antiaging.- Prospective.