Atracurium
CHF 43.20
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R1U1A3P449K
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Geliefert zwischen Mi., 05.11.2025 und Do., 06.11.2025
Details
Atracurium is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Side effects owing to histamine liberation are rash, reflex increase in heart rate, low blood pressure and bronchospasm. It is a bisbenzyltetrahydroisoquinolinium mixture of 10 stereoisomers. Atracurium was first synthesized, in 1974 by George H. Dewar, in John B. Stenlake's medicinal chemistry research group at Strathclyde University, Scotland. It is the first non-depolarising non-steroidal skeletal muscle relaxant rationally designed to undergo chemodegradation in vivo. Atracurium was licensed to Burroughs Wellcome Co., which developed atracurium and eventually marketed it (as a mixture of all ten stereoisomers) under the name Tracrium. Atracurium's rate of degradation in vivo is influenced by pH and temperature.
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GarantieWeitere Informationen
- Allgemeine Informationen
- Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
- Titel Atracurium
- Format Fachbuch
- EAN 9786130790455
- Genre Medizin
- Anzahl Seiten 100
- Herausgeber Alphascript Publishing
- GTIN 09786130790455
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