Autoimmune hemolytic anemias in children

This book examines the characteristics of autoimmune hemolytic anemias in children, based on a retrospective study of pediatric patients with a positive direct Coombs test. Epidemiological, clinical, biological and therapeutic data were analyzed using SPSS software. A total of 17 patients were included (10 girls and 7 boys), with an average age of three years. The most frequent etiologies identified were visceral leishmaniasis (5 cases) and beta-thalassemia major (4 cases). In addition to transfusions, corticosteroid therapy was administered to 10 of the 17 patients, with cure observed in 4 cases (23.5%). Although viral infections are generally considered to be the main causes of these anemias, our study revealed a predominance of visceral leishmaniasis, an etiology rarely mentioned in the literature. Autoimmune hemolytic anemias remain rare pathologies, often associated with a poor prognosis. A thorough etiological investigation and complete immunohematological workup are essential to optimize therapeutic management.

Autorentext

Als außerordentliche Professorin für biologische Hämatologie widme ich mich in meiner Laufbahn der Erforschung und Untersuchung seltener Krankheiten, insbesondere bei Kindern. Meine Leidenschaft und meine praktische Erfahrung in einem Transfusionszentrum zielen darauf ab, die Behandlung von Patienten mit hämatologischen Erkrankungen zu optimieren.