Basement Membrane Biology

Basement membranes are thin, extracellular matrices which separate the epithelia from their underlying connective tissue. Basement membrane has been viewed as a complex structure with its chemical composition varying, depending on the site of presentation. The principle constituents being collagenous proteins and non-collagenous substances like heparin sulphate proteoglycan, laminin, fibronectin, entactin or nidogen. By virtue of its anatomical location and highly complex composition, the basement membrane may have a key role in a wide range of epithelial-mesenchymal interactions. Basement membrane is considered to be a mirror that reflects the state of health or disease being altered in many disease processes. This book is a compilation of the structure, function and variations of basement membrane in health and disease.

Autorentext

Dr. Amitha J Lewis has completed her Masters in Oral Pathology and Microbiology in the year 2010. She is currently working as an Assistant Professor in Manipal College of Dental Sciences, Mangalore, MANIPAL UNIVERSITY.