Basics of Combinatorial Chemistry

Combinatorial chemistry encompasses the techniques, which enable synthesis of molecules en masse can be synthesized and tested for biological activity. By accelerating the process of chemical synthesis, this method is having a profound effect on all branches of chemistry, but especially on drug discovery. It has generated massive numbers of targeted molecules for testing and the developing techniques of high throughput screening have automated the screening process so larger numbers of biological assays can be done. All this together has reduced the discovery-to-market time from what used to be 10-14 years to 5-8 years. This book provides an overview on the basics of combinatorial synthesis.It will be useful for students and teachers of the drug discovery related courses like Diploma and Bachelor's in Pharmacy, Chemoinformatics, etc.

Autorentext

Hinna Hamid is an organic chemist by training and works on various aspects of medicinal Chemistry. Her research interests are Isolation and characterization of bioactive metabolites from natural sources and to develop novel synthetic methods and molecules to be used in the area of medicinal chemistry.