Bioactive Conformation I

Klappentext

This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts it is still valid and useful after 5 or 10 years. More information as well as the electronic version of the whole content available at: springerlink.com. The book will appeal to scientists and practitioners in the mentioned fields and in industry.

Inhalt
Spatial Screening for the Identification of the Bioactive Conformation of Integrin Ligands.- Dynamics and Thermodynamics of LigandProtein Interactions.- The Fibroblast Growth Factor (FGF) FGF Receptor Complex: Progress Towards the Physiological State.- Characterization of Interactions Between Misfolding Proteins and Molecular Chaperones by NMR Spectroscopy.- NMR Analysis of Bioprotective Sugars: Sucrose and Oligomeric (1?2)-?-D-glucopyranosyl-(1?2)-?-D-fructofuranosides.- Residual Dipolar Couplings Report on the Active Conformation of Rhodopsin-Bound Protein Fragments.- Glycosyltransferase Structure and Function.- Exploiting Ligand and Receptor Adaptability in Rational Drug Design Using Dynamics and Structure-Based Strategies.