Bioinorganic Chemistry

Klappentext The study of the chemistry of living processes - biochemistry - has traditionally centered on the behavior of organic chemical compounds in water, the principle solvent in all cells. Organic compounds and water account for 99 % of the matter in living systems. Some 20 inorganic elements are also essential for life, and they are found in similar amounts in most living systems. Bioinorganic Chemistry is essentially the border between inorganic chemistry and biology. The overall purpose of bioinorganic research is to study the relationship between inorganic metal ions such as copper and iron, and biologically specific macromolecules, experimentally as well as theoretically. The importance of inorganic chemistry in biology, especially metal ion coordination, has gained considerable attention during the last decade. The discoveries of the roles of metal ions and metalloproteins in health and disease through genetic and biochemical studies have drawn the attention of both inorganic chemists and molecular and cell biologists. Bioinorganic courses deal with the specific properties of metal ions as expressed in the functioning of biochemical systems, with the objective to deepen student insight into the chemical behaviour of metal ions in biological systems. Ochiai is generally considered the father of the discipline. When first published in 1977, the very successful first edition provided a clear and concise introduction to the brand new field of bioinorganic chemistry. Zusammenfassung Provides specialists! students! and general readers with an understanding of the basic chemistry of interactions of inorganic substances with biological systems at the molecular level. This book presents bioinorganic concepts in context and brings a distinct chemistry perspective to the subject. Inhaltsverzeichnis 0. Basics of Bio/ecosystems and Biochemistry, and Other Basic Concepts 1. Distribution of Elements 2. Biological Necessity for and the Behaviors of Inorganic Elements 3. How Do Enzymes Work? 4. Reactions of Acid-Base Type and Functions of Metal Cations 5. Reactions of Oxidation-Reduction Type including Electron Transfer Processes 6. Oxygen-Carrying Processes and Oxygenation Reactions 7. Metal-Involving Free Radical Reactions 8. Nitrogen Fixation 9. Other Essential Elements 10. Metal-related Physiology 11. Environmental Bioinorganic Chemistry 12. Medical Applications of Inorganic Compounds: Medicinal Inorganic Chemistry...

Autorentext
Eiichiro Ochiai was born in Tokyo and earned his PhD from the University of Tokyo. He has taught and carried out research in chemistry at universities in Japan, Canada, the USA and Sweden. At the time his area of research, bioinorganic chemistry, was a new field and he has published several books.

Zusammenfassung
Provides specialists, students, and general readers with an understanding of the basic chemistry of interactions of inorganic substances with biological systems at the molecular level. This book presents bioinorganic concepts in context and brings a distinct chemistry perspective to the subject.

Inhalt

0. Basics of Bio/ecosystems and Biochemistry, and Other Basic Concepts
   
   1. Distribution of Elements
   2. Biological Necessity for and the Behaviors of Inorganic Elements
   3. How Do Enzymes Work?
   4. Reactions of Acid-Base Type and Functions of Metal Cations
   5. Reactions of Oxidation-Reduction Type including Electron Transfer Processes
   6. Oxygen-Carrying Processes and Oxygenation Reactions
   7. Metal-Involving Free Radical Reactions
   8. Nitrogen Fixation
1. Other Essential Elements
   
   10. Metal-related Physiology
   11. Environmental Bioinorganic Chemistry
   12. Medical Applications of Inorganic Compounds: Medicinal Inorganic Chemistry