Bioprocess Engineering

Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations.

The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability.

The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.

Autorentext
Dr. Shijie Liu is a Professor of bioprocess engineering at the State University of New York - College of Environmental Science and Forestry (SUNY ESF). He graduated from Chengdu University of Science and Technology (now Sichuan University) with a BSc. majored in Chemical Engineering. His PhD in Chemical Engineering was earned from University of Alberta. Dr. Liu has 30 years of experience in academia and 5 years of experience in industry. He is a fellow of AIChE, and published over 200 scholarly papers. Earned a spot on the prestigious Top 2% Most Influential Scientists list by Stanford University and Elsevier. Current active research areas include Stem Cells, Fermentation, Biomolecular Kinetics, Bioreactors, Design of Experiments (for Quality Control and Kinetic Analysis). Taught Biomolecular Kinetics, Biochemical Reaction Engineering, Bioprocess Engineering of Reactions, among other courses over the past 20 years.

Inhalt

1. Introduction2. An Overview of Biological Basics3. An Overview of Chemical Reaction Analysis4. Batch Reactor5. Ideal Flow Reactors6. Kinetic Theory and Reaction Kinetics7. Parametric EstimationChapter8. Enzymes9. Allosteric Enzymes and Regulations10. Adsorption11. Catalysis and Chemical Reactions on Solid Surfaces12. Cell Growth and Metabolism13. Kinetics of Cell Growth and Batch Cultivation14. Cell Growth and Fermentation15 Ideal Fed-Batch Reactor16. Evolution and Genetic Engineering17. Sustainability: Perspective18 Sustainability and Stability19. Mass Transfer Effects: Immobilized and Heterogeneous Reaction Systems20. Bioreactor Design and Operation21. Bioprocess Kinetics Experimental Design22. Bioprocess Safety