Bone Marrow-Derived Progenitors

Includes supplementary material: sn.pub/extras

Klappentext

The ambitious goal of this volume is to provide in chapters written by accomplished scientists and experts in their field a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. With excitement generated almost daily about the possible uses of stem cells to treat human disease, but the controversy surrounding their use still raging, adult bone-marrow derived cells are more readily available, and have a staggering range of uses.

Zusammenfassung

The ambitious goal of this volume is to provide in chapters written by accomplished scientists and experts in their field a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. With excitement generated almost daily about the possible uses of stem cells to treat human disease, but the controversy surrounding their use still raging, adult bone-marrow derived cells are more readily available, and have a staggering range of uses.

Inhalt
Basic Principles.- Mobilization of Bone Marrow-Derived Progenitors.- Role of Endothelial Nitric Oxide in Bone Marrow-Derived Progenitor Cell Mobilization.- Immune Plasticity of Bone Marrow-Derived Mesenchymal Stromal Cells.- Bone Marrow-Derived Cells: The Influence of Aging and Cellular Senescence.- Involvement of Marrow-Derived Endothelial Cells in Vascularization.- Therapeutic Implication and Clinical Experience.- Comparison of Intracardiac Cell Transplantation: Autologous Skeletal Myoblasts Versus Bone Marrow Cells.- Ischemic Tissue Repair by Autologous Bone Marrow-Derived Stem Cells: Scientific Basis and Preclinical Data.- Cell Therapy and Gene Therapy Using Endothelial Progenitor Cells for Vascular Regeneration.- Mesenchymal Stem Cells for Cardiac Regenerative Therapy.- Autotransplantation of Bone Marrow-Derived Stem Cells as a Therapy for Neurodegenerative Diseases.- Stem Cells as a Treatment for Chronic Liver Disease and Diabetes.- The Participation of Mesenchymal Stem Cells in Tumor Stroma Formation and Their Application as Targeted-Gene Delivery Vehicles.