Cadmium: From Toxicity to Essentiality

Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted.

Provides an up-to-date information on the role of cadmium in life Covers the toxicology of cadmium including its effect on cancer Describes the essentiality of cadmium for marine microorganisms Describes the analytical tools needed for cadmium studies of biological samples Describes the biogeochemistry of cadmium, its release into the environment and effects on plants

Klappentext

Cadmium: From Toxicity to Essentiality, MILS-11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113 Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted. The book terminates with a fascinating report on the use of Cd(II) in carbonic anhydrase of certain marine phytoplankton species.

Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry . Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems*.*

Inhalt

1. The Bioinorganic Chemistry of Cadmium in the Context of Its Toxicity. - 2. Biogeochemistry of Cadmium and Its Release to the Environment. - 3. Speciation of Cadmium in the Environment. - 4. Determination of Cadmium in Biological Samples. - 5. Imaging and Sensing of Cadmium in Cells. - 6. Use of 113 Cd NMR to Probe the Native Metal Binding Sites in Metalloproteins: An Overview. - 7. Solid State Structures of Cadmium Complexes with Relevance for Biological Systems. - 8 . Complex Formation of Cadmium(II) with Sugar Residues, Nucleobases, Phosphates, Nucleotides, and Nucleic Acids. - 9. Cadmium(II) Complexes of Amino Acids and Peptides. - 10. Natural and Artificial Proteins Containing Cadmium. - 11. Cadmium in Metallothioneins. - 12. Cadmium-Accumulating Plants. - 13. Cadmium Toxicity in Plants. - 14. Toxicology of Cadmium and Its Damage to Mammalian Organs. - 15. Cadmium and Cancer. - 16. Cadmium in Marine Phytoplankton. Natural and Artificial Proteins Containing Cadmium. - 11. Cadmium in Metallothioneins. - 12. Cadmium-Accumulating Plants. - 13. Cadmium Toxicity in Plants. - 14. Toxicology of Cadmium and Its Damage to Mammalian Organs. - 15. Cadmium and Cancer. - 16. Cadmium in Marine Phytoplankton. Cadmium and Cancer. - 16. Cadmium in Marine Phytoplankton.