Cancer Genetics

This is a collection of chapters covering the key recent developments in cancer genetics which have an impact on clinical care. The target audience is physicians and scientists who need to be apprised on the most recent developments in the field.

Cancer Genetics is a collection of chapters covering the key recent developments in cancer genetics which have an impact on clinical care. The target audience will be physicians and scientists who need to be apprised on the most recent developments in the field.

Covers genetic susceptibility to gastric cancer, ethical issues related to cancer genetics, the role of common variants in the development of breast cancer, novel genetic findings related to neuroblastoma, and the role of constitutively decreased TGF-beta signaling The impact of genetics and its role in several cancers is becoming more defined A review of these biological relationships is covered by a panel of distinguished researchers and clinicians in their respective areas of research Includes supplementary material: sn.pub/extras

Klappentext
Cancer genetics has revolutionized the practice of medicine as inherited genetic information helps predicts which individuals are at risk of developing various forms of cancer. Furthermore, somatically acquired genetic changes help identify therapeutic targets for patients with several common tumor types such as breast and colon cancer. Cancer Genetics reviews seminal discoveries such as genetic susceptibility to gastric cancer, ethical issues related to cancer genetics, the role of common variants in the development of breast cancer, novel genetic findings related to neuroblastoma, and the role of constitutively decreased TGF-beta signaling, which is emerging as one of the most common causes of colorectal cancer. The book has been written for all clinicians and researchers interested in cancer genetics, including oncologists, genetic counselors and cancer researchers both in academia and in industry. "Genetic alterations are a fundamental component of all cancers. This text highlights critical issues relevant for both basic scientists and clinicians. Recognized thought leaders in the field discuss current knowledge and future challenges." - Steven T. Rosen, M.D., Series Editor

Zusammenfassung
Cancer Genetics is a collection of chapters covering the key recent developments in cancer genetics which have an impact on clinical care. The target audience will be physicians and scientists who need to be apprised on the most recent developments in the field.

Inhalt
Ethicolegal Aspects of Cancer Genetics.- The Influence of Common Polymorphisms on Breast Cancer.- Hereditary Diffuse Gastric Cancer.- Genetics and Genomics of Neuroblastoma.- TGF-? Signaling Alterations and Colon Cancer.