CAR-T Manufacturing

This edited volume describes innovations in all steps of the CAR-T manufacturing chain. These vital descriptions will help practitioners to overcome current challenges during the process and vastly reduce costs and enable timely and accessible administration of CAR-T therapy to patients.

Autorentext

Andy Tay is a Presidential Young Professor in the Department of Biomedical Engineering at the National University of Singapore (NUS) and Principal Investigator at the Institute of Health Innovation & Technology and NUS Tissue Engineering Programme. He obtained his Bachelor's degree from NUS and his PhD from UCLA in 2014 and 2017, respectively.

Inhalt

1. Immune cell selection and Isolation 2. Strategies for T cell Activation 3. Genetic tools to engineer CAR-T cells: Lessons from clinical studies 4. Intracellular delivery methods for therapeutic immune T-cell engineering 5. Bioreactor technology for CAR T cell manufacturing 6. Quality Control of CAR-T Products 7. Advances for in vivo CAR-T manufacturing